A method for protein secondary structure prediction
نویسندگان
چکیده
منابع مشابه
A pentapeptide-based method for protein secondary structure prediction.
We present a new method for protein secondary structure prediction, based on the recognition of well-defined pentapeptides, in a large databank. Using a databank of 635 protein chains, we obtained a success rate of 68.6%. We show that progress is achieved when the databank is enlarged, when the 20 amino acids are adequately grouped in 10 sets and when more pentapeptides are attributed one of th...
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Protein secondary structure can be used to help determine the tertiary structure via the fold recognition. Predicting the secondary structure from the protein sequence has attracted the attention of many researchers. Support Vector Machine (SVM) is a new learning algorithm based on statistical learning theory that has been successfully applied to the protein secondary structure prediction probl...
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Sequence alignment methods are very e ective for secondary structure prediction. However, they are only applicable when the similarity of the sequences is high enough. We previously reported that the extended sequence alignment method, which uses not only amino acid letters but also strings of amino acid letters representing motifs as comparing units, enabled us to nd common motifs even among t...
متن کاملProtein secondary structure prediction.
The past year has seen a consolidation of protein secondary structure prediction methods. The advantages of prediction from an aligned family of proteins have been highlighted by several accurate predictions made 'blind', before any X-ray or NMR structure was known for the family. New techniques that apply machine learning and discriminant analysis show promise as alternatives to neural networks.
متن کاملProtein Secondary Structure Prediction: a Literature Review with Focus on Machine Learning Approaches
DNA sequence, containing all genetic traits is not a functional entity. Instead, it transfers to protein sequences by transcription and translation processes. This protein sequence takes on a 3D structure later, which is a functional unit and can manage biological interactions using the information encoded in DNA. Every life process one can figure is undertaken by proteins with specific functio...
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ژورنال
عنوان ژورنال: Biopolymers and Cell
سال: 1998
ISSN: 0233-7657,1993-6842
DOI: 10.7124/bc.0004c9